Use of Prone Positioning in Nonintubated Patients With COVID-19 and Hypoxemic Acute Respiratory Failure

Xavier Elharrar; Youssef Trigui; Anne-Marie Dols; François Touchon; Stéphanie Martinez; Eloi Prud'homme; Laurent Papazian

doi:10.1001/jama.2020.8255

Use of Prone Positioning in Nonintubated Patients With COVID-19 and Hypoxemic Acute Respiratory Failure

JAMA. 2020 Jun 9;323(22):2336-2338. doi: 10.1001/jama.2020.8255.

Authors

Xavier Elharrar¹, Youssef Trigui¹, Anne-Marie Dols², François Touchon¹, Stéphanie Martinez¹, Eloi Prud'homme³, Laurent Papazian⁴

Affiliations

¹ Service des Maladies Respiratoires, Centre Hospitalier d'Aix-en-Provence, Aix-en-Provence, France.
² Faculté de médecine, Université Grenoble Alpes, Grenoble, France.
³ Médecine Intensive Réanimation, Assistance Publique-Hôpitaux de Marseille, Marseille, France.
⁴ Centre d'Etudes et de Recherches sur les Services de Santé et qualité de vie EA 3279, Aix-Marseille Université, Marseille, France.

Abstract

This case series describes the proportion of awake, nonintubated inpatients with COVID-19 and hypoxemic respiratory failure requiring oxygen supplementation whose Pao₂ increased ≥20% with prone positioning, and their respiratory status after resuming supine positioning.

MeSH terms

Acute Disease
Aged
Betacoronavirus*
COVID-19
Coronavirus Infections / complications
Coronavirus Infections / therapy*
Female
Humans
Hypoxia / etiology
Male
Middle Aged
Organ Dysfunction Scores
Oxygen / blood
Oxygen Inhalation Therapy*
Pandemics
Pneumonia, Viral / complications
Pneumonia, Viral / therapy*
Prone Position* / physiology
Prospective Studies
Respiratory Insufficiency / etiology
Respiratory Insufficiency / therapy*
SARS-CoV-2

Substances

Oxygen