The use of an inexpensive processing aid device (the Mouse PAD) to facilitate rodent tissue banking

Biotechniques. 2020 Jul;69(1):364-368. doi: 10.2144/btn-2019-0069. Epub 2020 May 18.

Abstract

The generation of an experimental animal model often requires considerable investment of both time and money. Typically, investigators are interested in specific organs and when experimental animals are euthanized, tissues that are not the focus of the research project are discarded. However, the remaining tissues from these animals could provide valuable scientific information if efficient, error-proof and economical approaches to collect and biobank them were available. We have developed a device that, when incorporated into our tissue processing workflow, allows for high-throughput collection and processing of multiple rodent organ systems. This device, the mouse Processing Aid Device, or mouse PAD, helps to standardize organ collection and increase its efficiency.

Keywords: 3D printing; biobanking; device design; necropsy; rodents; tissue harvest.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Models, Animal
  • Printing, Three-Dimensional
  • Rodentia
  • Tissue Banks*