Cytotoxic T Cells Are Replaced by Novel Clones After Immune Checkpoint Blocker Therapy

J Cutan Med Surg. 2020 May/Jun;24(3):314-315. doi: 10.1177/1203475419890843.
No abstract available

Keywords: BCC; SCC; immune checkpoint blockers; tumor infiltrating lymphocytes; tumor response.

Publication types

  • Letter

MeSH terms

  • Antibodies, Monoclonal, Humanized / immunology
  • Antibodies, Monoclonal, Humanized / pharmacology
  • Antibodies, Monoclonal, Humanized / therapeutic use
  • Antineoplastic Agents, Immunological / immunology
  • Antineoplastic Agents, Immunological / pharmacology
  • Antineoplastic Agents, Immunological / therapeutic use
  • Clone Cells / drug effects
  • Clone Cells / immunology*
  • Humans
  • Immune Checkpoint Inhibitors / immunology*
  • Immune Checkpoint Inhibitors / pharmacology
  • Immune Checkpoint Inhibitors / therapeutic use
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / immunology*
  • T-Lymphocytes, Cytotoxic / drug effects
  • T-Lymphocytes, Cytotoxic / immunology*
  • Tumor Microenvironment / drug effects*
  • Tumor Microenvironment / immunology

Substances

  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents, Immunological
  • Immune Checkpoint Inhibitors
  • cemiplimab