Associations Between Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blocker Use, Gastrointestinal Symptoms, and Mortality Among Patients With COVID-19

Nian-Di Tan; Yun Qiu; Xiang-Bin Xing; Subrata Ghosh; Min-Hu Chen; Ren Mao

doi:10.1053/j.gastro.2020.05.034

Associations Between Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blocker Use, Gastrointestinal Symptoms, and Mortality Among Patients With COVID-19

Gastroenterology. 2020 Sep;159(3):1170-1172.e1. doi: 10.1053/j.gastro.2020.05.034. Epub 2020 May 16.

Authors

Nian-Di Tan¹, Yun Qiu², Xiang-Bin Xing¹, Subrata Ghosh³, Min-Hu Chen⁴, Ren Mao⁵

Affiliations

¹ Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; COVID-19 Medical Team, West Campus of Wuhan Union Hospital, Wuhan, China.
² Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
³ National Institute for Health Research Biomedical Research Institute, Institute of Translational Medicine, University of Birmingham, Birmingham, United Kingdom; University Hospitals Birmingham National Health Service Foundation Trust, United Kingdom.
⁴ Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. Electronic address: [email protected].
⁵ Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. Electronic address: [email protected].

No abstract available

Keywords: ACE, angiotensin-converting enzyme; ACEI, angiotensin-converting enzyme inhibitors; ACEI/ARB; ARB, angiotensin receptor blockers; COVID-19; COVID-19, coronavirus disease 2019; Digestive System; GI, gastrointestinal; Liver Injury.

MeSH terms

Aged
Angiotensin Receptor Antagonists / therapeutic use*
Angiotensin-Converting Enzyme Inhibitors / therapeutic use*
Betacoronavirus*
COVID-19
China
Coronavirus Infections / complications*
Coronavirus Infections / diagnosis
Coronavirus Infections / mortality*
Female
Gastrointestinal Diseases / epidemiology*
Humans
Hypertension / drug therapy
Length of Stay
Male
Middle Aged
Pandemics
Pneumonia, Viral / complications*
Pneumonia, Viral / diagnosis
Pneumonia, Viral / mortality*
Retrospective Studies
SARS-CoV-2
Survival Rate
Symptom Assessment

Substances

Angiotensin Receptor Antagonists
Angiotensin-Converting Enzyme Inhibitors