A microbiological survey of cervical and vaginal smears associated with a serological survey of sexual diseases was carried out on 298 prostitutes at the four principal Malagasy sea ports. This survey leads us to these conclusions: The great frequency of specific inflammations (72.1%) with Trichomonas vaginalis in the first place (39.2%). The serological tests proved a high rate of positive treponemical serologies (25.2%), whose the half of the cases are evolutive forms. Nevertheless prevalence of HBs-antigene among this population does not exceed the rate recorded in the other African countries, while the rate of anti HIV antibodies' carriers is lower than the rates recorded in those African countries. A comparative survey with tests carried out at IPM on Malagasy women showed clearly higher figures of inflammations, cervical and vaginal infections and positive treponemical serologies among prostitutes.