Evaluation and Management of Nonculprit Lesions in STEMI

Troels Thim; Nina W van der Hoeven; Carmine Musto; Robin Nijveldt; Matthias Götberg; Thomas Engstrøm; Pieter C Smits; Keith G Oldroyd; Anthony H Gershlick; Javier Escaned; Sergio Bravo Baptista; Luis Raposo; Niels van Royen; Michael Maeng

doi:10.1016/j.jcin.2020.02.030

Evaluation and Management of Nonculprit Lesions in STEMI

JACC Cardiovasc Interv. 2020 May 25;13(10):1145-1154. doi: 10.1016/j.jcin.2020.02.030.

Authors

Affiliations

¹ Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark. Electronic address: [email protected].
² Department of Cardiology, Amsterdam UMC, Amsterdam, the Netherlands.
³ Department of Interventional Cardiology, San Camillo Hospital, Rome, Italy.
⁴ Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands.
⁵ Department of Cardiology, Clinical Sciences, Lund University, Skåne University Hospital, Lund, Sweden.
⁶ Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
⁷ Department of Cardiology, Maasstad Ziekenhuis, Rotterdam, the Netherlands.
⁸ Department of Cardiology, Golden Jubilee National Hospital, Glasgow, United Kingdom.
⁹ University of Leicester, University Hospitals of Leicester, Leicester Biomedical Research Unit, Leicester, United Kingdom.
¹⁰ Hospital Clinico San Carlos IDISSC, Complutense University, Madrid, Spain.
¹¹ University Clinic of Cardiology, Faculty of Medicine at University of Lisbon, Hospital Prof. Doutor Fernando Fonseca, Amadora, Portugal.
¹² Cardiology Department, Santa Cruz Hospital-CHLO, Lisbon, Portugal.
¹³ Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.

PMID: 32438985
DOI: 10.1016/j.jcin.2020.02.030

Abstract

Nonculprit lesions are frequently observed in patients with ST-segment elevation myocardial infarction. Results from recent randomized clinical trials suggest that complete revascularization after ST-segment elevation myocardial infarction improves outcomes. In this state-of-the-art paper, the authors review these trials and consider how best to determine which nonculprit lesions require revascularization and when this should be performed.

Keywords: CFR; FFR; STEMI; iFR; nonculprit coronary lesions.

Publication types

Review

MeSH terms

Clinical Decision-Making
Coronary Artery Disease / diagnostic imaging
Coronary Artery Disease / physiopathology
Coronary Artery Disease / therapy*
Coronary Circulation
Coronary Stenosis / diagnostic imaging
Coronary Stenosis / physiopathology
Coronary Stenosis / therapy*
Humans
Percutaneous Coronary Intervention* / adverse effects
Recovery of Function
Recurrence
Risk Factors
ST Elevation Myocardial Infarction / diagnostic imaging
ST Elevation Myocardial Infarction / physiopathology
ST Elevation Myocardial Infarction / therapy*
Severity of Illness Index
Treatment Outcome