Utilization of LC-MS to Determine Monoclonal Gammopathy-Associated Granulocyte Macrophage Colony Stimulating Factor Antibody and Novel Treatment of Pulmonary Alveolar Proteinosis

J Appl Lab Med. 2020 Mar 1;5(2):394-400. doi: 10.1093/jalm/jfz024.
No abstract available

Keywords: alveolar proteinosis; antibody; mass spectrometry; monoclonal gammopathy of unknown significance; nocardiosis.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Monoclonal / blood
  • Antibodies, Monoclonal / immunology*
  • Autoantibodies / blood
  • Autoantibodies / immunology
  • Biopsy
  • Bone Marrow / pathology
  • Chromatography, Liquid
  • Granulocyte-Macrophage Colony-Stimulating Factor / antagonists & inhibitors*
  • Granulocyte-Macrophage Colony-Stimulating Factor / immunology*
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin G / immunology
  • Immunoglobulin gamma-Chains / blood
  • Immunoglobulin gamma-Chains / immunology
  • Male
  • Monoclonal Gammopathy of Undetermined Significance / blood
  • Monoclonal Gammopathy of Undetermined Significance / diagnosis
  • Monoclonal Gammopathy of Undetermined Significance / immunology
  • Paraproteinemias / blood
  • Paraproteinemias / diagnosis*
  • Paraproteinemias / immunology*
  • Pulmonary Alveolar Proteinosis / diagnosis
  • Pulmonary Alveolar Proteinosis / drug therapy*
  • Pulmonary Alveolar Proteinosis / etiology
  • Tandem Mass Spectrometry
  • Tomography, X-Ray Computed

Substances

  • Antibodies, Monoclonal
  • Autoantibodies
  • Immunoglobulin G
  • Immunoglobulin gamma-Chains
  • Granulocyte-Macrophage Colony-Stimulating Factor