Paediatric antimicrobial stewardship programmes in the UK's regional children's hospitals

S Vergnano; A Bamford; S Bandi; F Chappel; A Demirjian; K Doerholt; M Emonts; L Ferreras-Antolin; A Goenka; L Jones; J A Herberg; L Hinds; O McGarrity; P Moriarty; S O'Riordan; M Patel; S Paulus; D Porter; K Stock; S Patel

doi:10.1016/j.jhin.2020.05.030

Paediatric antimicrobial stewardship programmes in the UK's regional children's hospitals

J Hosp Infect. 2020 Aug;105(4):736-740. doi: 10.1016/j.jhin.2020.05.030. Epub 2020 Jun 11.

Authors

S Vergnano¹, A Bamford², S Bandi³, F Chappel⁴, A Demirjian⁴, K Doerholt⁵, M Emonts⁶, L Ferreras-Antolin⁵, A Goenka⁷, L Jones⁸, J A Herberg⁹, L Hinds¹⁰, O McGarrity², P Moriarty¹¹, S O'Riordan¹², M Patel¹³, S Paulus¹⁴, D Porter¹⁵, K Stock¹⁶, S Patel¹⁷

Affiliations

¹ University of Bristol, Bristol, UK; Bristol Royal Hospital for Children, Bristol, UK. Electronic address: [email protected].
² Great Ormond Street Hospital for Children NHS Trust, London, UK.
³ Leicester Royal Infirmary, Leicester, UK.
⁴ Evelina London Children's Hospital, London, UK.
⁵ St George's Hospital, London, UK.
⁶ The Great North Children's Hospital, Newcastle, UK.
⁷ Royal Manchester Children's Hospital, Manchester, UK.
⁸ Royal Hospital for Sick Children, Edinburgh, UK.
⁹ Imperial College, London, UK.
¹⁰ Sheffield Children's Hospital, London, UK.
¹¹ Royal Belfast Hospital for Sick Children, Northern Ireland, Belfast, UK.
¹² Leeds Children's Hospital, Leeds, UK.
¹³ Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.
¹⁴ John Radcliffe Hospital, Oxford, UK.
¹⁵ Alder Hey Children's NHS Foundation Trust, Liverpool, UK.
¹⁶ Royal Hospital for Children, Glasgow, UK.
¹⁷ Southampton Children's Hospital, Southampton, UK.

PMID: 32454075
DOI: 10.1016/j.jhin.2020.05.030

Abstract

A survey was conducted in UK regional children's hospitals with paediatric intensive care and paediatric infectious disease (PID) departments to describe the characteristics of paediatric antimicrobial stewardship (PAS) programmes. A structured questionnaire was sent to PAS coordinators. 'Audit and feedback' was implemented in 13 out of 17 centres. Microbiology-led services were more likely to implement antimicrobial restriction (75% vs 33% in PID-led services), to focus on broad-spectrum antibiotics, and to review patients with positive blood cultures. PID-led services were more likely to identify patients from e-prescribing or drug charts and review all antimicrobials. A PAS network has been established.

Keywords: Antimicrobial stewardship; Children; Paediatrics; Programme implementation.

Publication types

Multicenter Study

MeSH terms

Anti-Bacterial Agents / therapeutic use*
Antimicrobial Stewardship*
Child
Communicable Diseases / drug therapy
Health Plan Implementation*
Hospitals, Pediatric*
Humans
Intensive Care Units, Neonatal
Practice Patterns, Physicians'*
Surveys and Questionnaires
United Kingdom

Substances

Anti-Bacterial Agents