Acquired hemophilia A revealed by spontaneous bleeding in an 80-year-old man: a marginal diagnosis?

Acta Clin Belg. 2022 Feb;77(1):93-95. doi: 10.1080/17843286.2020.1768735. Epub 2020 May 27.

Abstract

This case report illustrates the difficulty associated with diagnosing acquired hemophilia A by reviewing the case of an 80-year-old man admitted to the hospital for anemia. A prolonged activated partial thromboplastin time (aPTT) was not noticed until the patient developed a severe hemorrhagic syndrome.

Keywords: Acquired hemophilia; bleeding disorder; factor VIII inhibitor; marginal zone lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Hemophilia A* / complications
  • Hemophilia A* / diagnosis
  • Hemorrhage / diagnosis
  • Hemorrhage / etiology
  • Humans
  • Male
  • Partial Thromboplastin Time