Reply to Letter to Editor from Veeravalli and Dash on "Tofacitinib Is a Mechanism-Based Inactivator of Cytochrome P450 3A4: Revisiting the Significance of the Epoxide Intermediate and Glutathione Trapping"

Chem Res Toxicol. 2020 Jul 20;33(7):1514-1515. doi: 10.1021/acs.chemrestox.0c00187. Epub 2020 Jun 16.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • Cytochrome P-450 CYP3A
  • Epoxy Compounds*
  • Glutathione*
  • Piperidines
  • Pyrimidines
  • Pyrroles

Substances

  • Epoxy Compounds
  • Piperidines
  • Pyrimidines
  • Pyrroles
  • tofacitinib
  • Cytochrome P-450 CYP3A
  • Glutathione