Chest X-ray features of SARS-CoV-2 in the emergency department: a multicenter experience from northern Italian hospitals

Respir Med. 2020 Aug-Sep:170:106036. doi: 10.1016/j.rmed.2020.106036. Epub 2020 May 22.

Abstract

Objectives: To evaluate the imaging features of routine admission chest X-ray in patients referred for novel Coronavirus 2019 infection.

Methods: All patients referred to the emergency departments, RT-PCR positive for SARS-CoV-2 infection were evaluated. Demographic and clinical data were recorded. Two radiologists (8 and 15 years of experience) reviewed all the X-ray images and evaluated the following findings: interstitial opacities, alveolar opacities (AO), AO associated with consolidation, consolidation and/or pleural effusion. We stratified patients in groups according to the time interval between symptoms onset (cut-off 5 days) and X-ray imaging and according to age (cut-off 60 years old). Computed tomography was performed in case of a discrepancy between clinical symptoms, laboratory and X-ray findings, and/or suspicion of complications.

Results: A total of 468 patients were tested positive for SARS-CoV-2. Lung lesions primarily manifested as interstitial opacities (71.7%) and AO opacities (60.5%), more frequently bilateral (64.5%) and with a peripheral predominance (62.5%). Patients admitted to the emergency radiology department after 5 days from symptoms onset, more frequently had interstitial and AO opacities, in comparison to those admitted within 5 days, and lung lesions were more frequently bilateral and peripheral. Older patients more frequently presented interstitial and AO opacities in comparison to younger ones. Sixty-eight patients underwent CT that principally showed the presence of ground-glass opacities and consolidations.

Conclusions: The most common X-ray pattern is multifocal and peripheral, associated with interstitial and alveolar opacities. Chest X-ray, compared to CT, can be considered a reliable diagnostic tool, especially in the Emergency setting.

Keywords: Coronavirus; Infections; Radiography; Tomography; X-ray computed.

Publication types

  • Multicenter Study

MeSH terms

  • Betacoronavirus / isolation & purification
  • COVID-19
  • COVID-19 Testing
  • Clinical Laboratory Techniques / methods
  • Comparative Effectiveness Research
  • Coronavirus Infections* / complications
  • Coronavirus Infections* / diagnosis
  • Coronavirus Infections* / epidemiology
  • Emergency Service, Hospital / statistics & numerical data
  • Female
  • Humans
  • Italy / epidemiology
  • Male
  • Middle Aged
  • Pandemics*
  • Pleural Effusion* / diagnostic imaging
  • Pleural Effusion* / etiology
  • Pneumonia, Viral* / complications
  • Pneumonia, Viral* / diagnosis
  • Pneumonia, Viral* / diagnostic imaging
  • Pneumonia, Viral* / epidemiology
  • Pneumonia, Viral* / etiology
  • Radiography, Thoracic* / methods
  • Radiography, Thoracic* / statistics & numerical data
  • Reproducibility of Results
  • SARS-CoV-2
  • Tomography, X-Ray Computed* / methods
  • Tomography, X-Ray Computed* / statistics & numerical data