Speeding tumor genotyping during the SARS-CoV-2 outbreak through liquid biopsy

Cancer. 2020 Sep 15;126(18):4089-4091. doi: 10.1002/cncr.32983. Epub 2020 May 30.

Abstract

This commentary proposes a shift in the current diagnostic workflow for patients with metastatic cancer to incorporate the use of liquid biopsy. This proposal, born in the time of a severe crisis for the health care system, might also be applied when the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) outbreak ends and thereby reduce the turnaround time for results from molecular testing for patients with cancer and increase the number of patients potentially benefiting from highly effective targeted therapies.

Keywords: COVID-19; SARS-CoV-2; cancer; cfDNA; liquid biopsy.

MeSH terms

  • COVID-19*
  • Cell-Free Nucleic Acids / blood
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Liquid Biopsy*
  • Neoplasms / genetics*
  • Neoplasms / pathology*
  • Phlebotomy
  • Workflow

Substances

  • Cell-Free Nucleic Acids