1 McMaster Children's Hospital, Hamilton, ON, Canada, and Department of Pediatrics, McMaster University, Hamilton, ON, Canada Stollery Children's Hospital, Alberta Health Services, Edmonton, AB, Canada McMaster Children's Hospital, Hamilton, ON, Canada Surrey Memorial Hospital & Jim Pattison Outpatient Care and Surgery Centre, Surrey, BC, Canada Department of Pharmacy, Victoria General Hospital, Vancouver Island Health Authority, Victoria, BC, Canada The Hospital for Sick Children, Toronto, ON, Canada Janeway Children's Health and Rehabilitation Centre, St. John's, NL, Canada IWK Health Centre, Halifax, NS, Canada Biostatistics Unit, St. Joseph's Healthcare, Hamilton, ON, Canada.