1H, 13C and 15N resonance assignments of Q38FZ4, hypothetical protein from Trypanosoma brucei

Biomol NMR Assign. 2020 Oct;14(2):255-257. doi: 10.1007/s12104-020-09956-5. Epub 2020 Jun 3.

Abstract

Q38FZ4 (UniProt accession number), is an 85-residue hypothetical protein from Trypanosoma brucei (T. brucei). Q38FZ4, which might be specific among the trypanosomatid genomes, shares low sequence similarity with mammal proteins and also has an essential function in the growth of T. brucei. Here we report the resonance assignments and secondary structure analysis of Q38FZ4 from T. brucei, which will lay the foundation for the protein structure determination and function elucidation.

Keywords: Q38FZ4; Resonance assignment; T. brucei; hypothetical protein.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbon-13 Magnetic Resonance Spectroscopy*
  • Nitrogen Isotopes
  • Protein Structure, Secondary
  • Proton Magnetic Resonance Spectroscopy*
  • Protozoan Proteins / analysis*
  • Trypanosoma brucei brucei / metabolism*

Substances

  • Nitrogen Isotopes
  • Nitrogen-15
  • Protozoan Proteins