Editorial: The Immunobiology of HLA-Haploidentical Hematopoietic Cell Transplantation

Antonella Mancusi; Christopher G Kanakry; Antonio Pierini

doi:10.3389/fimmu.2020.01031

Editorial: The Immunobiology of HLA-Haploidentical Hematopoietic Cell Transplantation

Front Immunol. 2020 May 20:11:1031. doi: 10.3389/fimmu.2020.01031. eCollection 2020.

Authors

Antonella Mancusi¹, Christopher G Kanakry², Antonio Pierini¹

Affiliations

¹ Hematology and Clinical Immunology and Bone Marrow Transplant Program, Department of Medicine, University of Perugia, Perugia, Italy.
² Experimental Transplantation and Immunotherapy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States.

No abstract available

Keywords: T-cell depleted grafts; T-cell-replete grafts; adoptive cell therapy; haploidentical transplantation; immune evasion; immune reconstitution; post-transplantation cyclophosphamide; regulatory T cells.

Publication types

Editorial
Introductory Journal Article
Research Support, N.I.H., Intramural
Research Support, Non-U.S. Gov't

MeSH terms

Cyclophosphamide / administration & dosage
Graft vs Host Disease / etiology
Graft vs Host Disease / prevention & control
HLA Antigens*
Hematopoietic Stem Cell Transplantation / adverse effects
Hematopoietic Stem Cell Transplantation / methods*
Hematopoietic Stem Cell Transplantation / trends
Humans
Immunosuppressive Agents / administration & dosage
T-Lymphocytes / immunology
Transplantation, Haploidentical / adverse effects
Transplantation, Haploidentical / methods*
Transplantation, Haploidentical / trends

Substances

HLA Antigens
Immunosuppressive Agents
Cyclophosphamide