Abstract
Geriatric inpatients with major depression received nortriptyline for 4 weeks. Plasma E-10-hydroxynortriptyline concentrations were correlated positively with residual Hamilton depression ratings and negatively with changes in ratings.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Aged
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Depressive Disorder / blood
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Depressive Disorder / drug therapy*
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Humans
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Middle Aged
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Nortriptyline / analogs & derivatives*
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Nortriptyline / blood
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Nortriptyline / therapeutic use*
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Time Factors
Substances
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10-hydroxynortriptyline
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Nortriptyline