Putting epigenetic biomarkers to the test for clinical trials

Elife. 2020 Jun 9:9:e58592. doi: 10.7554/eLife.58592.

Authors

Jamie N Justice^{1

2}, Stephen B Kritchevsky^{1

2}

Affiliations

¹ Internal Medicine Section on Gerontology and Geriatrics, Wake Forest School of Medicine, Winston-Salem, United States.
² Sticht Center for Healthy Aging and Alzheimer's Prevention, Wake Forest School of Medicine, Winston-Salem, United States.

Abstract

Reliable biomarkers are needed to test the effectiveness of interventions intended to improve health and extend lifespan.

Keywords: DNA methylation; aging; biological aging; epidemiology; epigenetic; global health; human; life-course.

© 2020, Justice and Kritchevsky.

MeSH terms

Age Factors
Biomedical Research
Clinical Trials as Topic / methods*
DNA Methylation*
Epigenesis, Genetic
Genetic Markers*
Geriatrics / methods
Humans

Substances

Genetic Markers