[Starvation ketoacidosis during prolonged fasting of 26 days]

Ann Biol Clin (Paris). 2020 Jun 1;78(3):323-328. doi: 10.1684/abc.2020.1553.
[Article in French]

Abstract

Ketosis is a metabolic situation involving an increase in blood and urine concentrations of ketones that, when prolonged, leads to acidosis. Moderate ketosis usually appears after a fast of a few hours, but its prolongation exposes to hyperketosis. Observation: A 25-year-old woman presented to the emergency department for cohercitive vomiting. She was fasting for a long time in a spiritual setting and had a restricted diet limited to water and vitamin supplements. Clinical and biological assessment was in favour of fasting ketoacidosis. Evolution was favorable with intravenous hydration, poly-ionic and micronutrient supplementation and a gradual resumption of oral feeding. Conclusion: We report the case of a patient with fasting ketoacidosis. Besides consequences of this ketoacidosis, the challenge was also in resuming oral feeding in order to avoid a potentially fatal inappropriate renutrition syndrome.

Keywords: ketone bodies; ketonemia; ketonuria; ketosis; refeeding syndrom; starvation.

Publication types

  • Case Reports

MeSH terms

  • Acidosis / blood
  • Acidosis / diagnosis
  • Acidosis / etiology
  • Acidosis / therapy
  • Adult
  • Fasting / adverse effects*
  • Fasting / blood
  • Female
  • Fluid Therapy
  • Humans
  • Ketosis / blood
  • Ketosis / diagnosis
  • Ketosis / etiology*
  • Ketosis / therapy
  • Parenteral Nutrition
  • Starvation / blood
  • Starvation / complications*
  • Starvation / therapy
  • Time Factors