Quo vadis microRNAs?

Bastian Fromm; Andreas Keller; Xiaozeng Yang; Marc R Friedlander; Kevin J Peterson; Sam Griffiths-Jones

doi:10.1016/j.tig.2020.03.007

Quo vadis microRNAs?

Trends Genet. 2020 Jul;36(7):461-463. doi: 10.1016/j.tig.2020.03.007. Epub 2020 Apr 16.

Authors

Bastian Fromm¹, Andreas Keller², Xiaozeng Yang³, Marc R Friedlander⁴, Kevin J Peterson⁵, Sam Griffiths-Jones⁶

Affiliations

¹ Science for Life Laboratory, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden. Electronic address: [email protected].
² Clinical Bioinformatics, Saarland Informatics Campus, Saarland University, Saarbrücken, Germany; Department of Neurobiology, School of Medicine, Stanford, CA, USA.
³ Beijing Agro-biotechnology Research Center, Beijing Key Laboratory of Agricultural Genetic Resources and Biotechnology, Beijing Academy of Agriculture and Forestry Sciences, Beijing, PR China.
⁴ Science for Life Laboratory, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.
⁵ Department of Biological Sciences, Dartmouth College, Hanover, NH, USA.
⁶ School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.

PMID: 32544447
DOI: 10.1016/j.tig.2020.03.007

Abstract

Since 2002, published miRNAs have been collected and named by the online repository miRBase. However, with 11 000 annual publications this has become challenging. Recently, four specialized miRNA databases were published, addressing particular needs for diverse scientific communities. This development provides major opportunities for the future of miRNA annotation and nomenclature.

Keywords: annotation; database; miRNAs; nomenclature; noncoding genes.

MeSH terms

Databases, Nucleic Acid*
Gene Expression Regulation*
Genomics
Humans
MicroRNAs / genetics*
Molecular Sequence Annotation / standards*
Sequence Analysis, RNA / standards*
Software*

Substances

MicroRNAs