Acute megakaryoblastic leukaemia with t(1;22)(p13·3;q13·1)/RBM15-MKL1 in an adult patient following a non-mediastinal germ cell tumour

Br J Haematol. 2020 Sep;190(6):e329-e332. doi: 10.1111/bjh.16900. Epub 2020 Jun 23.
No abstract available

Keywords: RBM15-MKL1; AMKL; acute megakaryoblastic leukaemia; germ cell tumor; t(1;22)(p13.3;q13.1).

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Chromosomes, Human, Pair 1* / genetics
  • Chromosomes, Human, Pair 1* / metabolism
  • Chromosomes, Human, Pair 22* / genetics
  • Chromosomes, Human, Pair 22* / metabolism
  • Humans
  • Leukemia, Megakaryoblastic, Acute* / genetics
  • Leukemia, Megakaryoblastic, Acute* / metabolism
  • Leukemia, Megakaryoblastic, Acute* / pathology
  • Male
  • Neoplasms, Germ Cell and Embryonal* / genetics
  • Neoplasms, Germ Cell and Embryonal* / metabolism
  • Neoplasms, Germ Cell and Embryonal* / pathology
  • Neoplasms, Second Primary* / genetics
  • Neoplasms, Second Primary* / metabolism
  • Neoplasms, Second Primary* / pathology
  • Oncogene Proteins, Fusion* / genetics
  • Oncogene Proteins, Fusion* / metabolism
  • Retroperitoneal Neoplasms* / genetics
  • Retroperitoneal Neoplasms* / metabolism
  • Retroperitoneal Neoplasms* / pathology
  • Translocation, Genetic*

Substances

  • OTT-MAL fusion protein, human
  • Oncogene Proteins, Fusion