Hypothesis: a role for tumor necrosis factor in immune-mediated demyelination and its relevance to multiple sclerosis

J Neuroimmunol. 1988 Apr;18(1):87-94. doi: 10.1016/0165-5728(88)90137-3.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Autoimmune Diseases / physiopathology*
  • Cell Survival / drug effects
  • Demyelinating Diseases / physiopathology*
  • Encephalomyelitis, Autoimmune, Experimental / immunology
  • Encephalomyelitis, Autoimmune, Experimental / physiopathology
  • Humans
  • Mice
  • Models, Biological*
  • Multiple Sclerosis / physiopathology*
  • Myelin Sheath / drug effects
  • Myelin Sheath / immunology
  • Rats
  • Rats, Inbred Lew
  • Recombinant Proteins / pharmacology
  • Tumor Necrosis Factor-alpha / physiology*

Substances

  • Recombinant Proteins
  • Tumor Necrosis Factor-alpha