Objective: To date, no cases have been reported on the effects of COVID-19 in laryngectomees.
Case presentation: We herein presented two clinical cases of laryngectomized patients affected by COVID-19, detailing their clinical course and complications.
Discussion: In our experience, permanent tracheostomy did not significantly affect the choice of treatment. However, dedicated devices and repeated tracheal toilettes may be needed to deal with oxygen-therapy-related tracheal crusting.
Conclusion: In conclusion, laryngectomees should be considered a vulnerable population that may be at risk for worse outcomes of COVID-19 due to anatomical changes in their airways. The role of the ENT specialist is to guide airway management and inform the support-staff regarding specific needs of these patients.
Keywords: COVID-19; SARS-CoV-2; coronavirus; laryngectomy; management.