Bronchoscopic Treatment of Tracheobronchial Fistula With Autologous Platelet-Rich Plasma

Meirong Wu; Huihuang Lin; Liyong Shi; Linlin Huang; Yawen Zhuang; Yiming Zeng

doi:10.1016/j.athoracsur.2020.05.047

Bronchoscopic Treatment of Tracheobronchial Fistula With Autologous Platelet-Rich Plasma

Ann Thorac Surg. 2021 Feb;111(2):e129-e131. doi: 10.1016/j.athoracsur.2020.05.047. Epub 2020 Jun 26.

Authors

Meirong Wu¹, Huihuang Lin¹, Liyong Shi¹, Linlin Huang¹, Yawen Zhuang¹, Yiming Zeng²

Affiliations

¹ Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China; Respiratory Medicine Center of Fujian Province, Quanzhou, China.
² Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China; Respiratory Medicine Center of Fujian Province, Quanzhou, China. Electronic address: [email protected].

PMID: 32599054
DOI: 10.1016/j.athoracsur.2020.05.047

Abstract

Tracheobronchial fistula (TBF) is a challenging management condition. Several bronchoscopic procedures have been tried for fistula closure. However, none has been found to be superior to the others. We herein describe a novel technique involving the submucosal injection of autologous platelet-rich plasma (auto-PRP) around the fistula to close the TBF. After auto-PRP treatment, all 3 TBF patients have successfully healed. No treatment-related complications and fistula-related symptoms were detected. Thus, this application of auto-PRP for fistula closure is a feasible and cost-effective strategy and could be recommended as a valuable therapeutic alternative for repairing postoperative TBF.

Publication types

Case Reports

MeSH terms

Aged
Bronchial Fistula / diagnosis
Bronchial Fistula / therapy*
Bronchoscopy / methods*
Fistula / diagnosis
Fistula / therapy
Humans
Male
Middle Aged
Platelet-Rich Plasma*
Tomography, X-Ray Computed
Tracheal Diseases / diagnosis
Tracheal Diseases / therapy*