COVID-19 in Patient with Sarcoidosis Receiving Long-Term Hydroxychloroquine Treatment, France, 2020

Emerg Infect Dis. 2020 Oct;26(10):2513-2515. doi: 10.3201/eid2610.201816. Epub 2020 Jul 1.

Abstract

Because of in vitro studies, hydroxychloroquine has been evaluated as a preexposure or postexposure prophylaxis for coronavirus disease (COVID-19) and as a possible COVID-19 curative treatment. We report a case of COVID-19 in a patient with sarcoidosis who was receiving long-term hydroxychloroquine treatment and contracted COVID-19 despite adequate plasma concentrations.

Keywords: 2019 novel coronavirus disease; COVID-19; France; SARS-CoV-2; coronavirus; coronavirus disease; hydroxychloroquine; plasma concentration; respiratory infections; sarcoidosis; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Antimalarials / blood
  • Antimalarials / therapeutic use*
  • COVID-19
  • Coronavirus Infections / complications*
  • Coronavirus Infections / diagnosis
  • France
  • Humans
  • Hydroxychloroquine / blood
  • Hydroxychloroquine / therapeutic use*
  • Male
  • Pandemics
  • Pneumonia, Viral / complications*
  • Pneumonia, Viral / diagnosis
  • Sarcoidosis, Pulmonary / complications*
  • Sarcoidosis, Pulmonary / drug therapy*
  • Time Factors
  • Tomography, X-Ray Computed

Substances

  • Antimalarials
  • Hydroxychloroquine