Concerns about how to use established minimal residual disease monitoring in the treatment of NPM1-mutant acute myeloid leukaemia (AML) following reduced intensity chemotherapy protocols for AML given as a result of the COVID-19 pandemic

Br J Haematol. 2020 Aug;190(4):e208-e210. doi: 10.1111/bjh.16985. Epub 2020 Jul 26.
No abstract available

Keywords: AML; MRD; acute leukaemia; molecular genetics; molecular haematology.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
  • COVID-19 Drug Treatment*
  • COVID-19* / blood
  • COVID-19* / genetics
  • Cytarabine / administration & dosage
  • Daunorubicin / administration & dosage
  • Gemtuzumab / administration & dosage
  • Humans
  • Leukemia, Myeloid, Acute* / blood
  • Leukemia, Myeloid, Acute* / drug therapy
  • Leukemia, Myeloid, Acute* / genetics
  • Male
  • Mutation*
  • Neoplasm, Residual
  • Nuclear Proteins / genetics*
  • Nucleophosmin
  • SARS-CoV-2*

Substances

  • NPM1 protein, human
  • Nuclear Proteins
  • Cytarabine
  • Nucleophosmin
  • Gemtuzumab
  • Daunorubicin