[Research Advances in the Association between Inflammasome and Abdominal Aortic Aneurysm]

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2020 Jun 30;42(3):393-398. doi: 10.3881/j.issn.1000-503X.11089.
[Article in Chinese]

Abstract

The inflammasome is a multiprotein complex localized in the cytoplasm.It can mediate the expressions of various inflammatory cytokines such as interleukin(IL)-1β and IL-18 and plays a key role in regulating inflammatory response.As sterile inflammation,abdominal aortic aneurysm currently can only be treated by surgery.This article reviews the research advances in the role of inflammasomes in abdominal aortic aneurysm.

Keywords: abdominal aortic aneurysm; inflammasome; inflammation.

Publication types

  • Review

MeSH terms

  • Aortic Aneurysm, Abdominal*
  • Humans
  • Inflammasomes*
  • Inflammation
  • Interleukin-1beta
  • NLR Family, Pyrin Domain-Containing 3 Protein

Substances

  • Inflammasomes
  • Interleukin-1beta
  • NLR Family, Pyrin Domain-Containing 3 Protein