Association of Digestive Symptoms and Hospitalization in Patients With SARS-CoV-2 Infection

Am J Gastroenterol. 2020 Jul;115(7):1129-1132. doi: 10.14309/ajg.0000000000000712.

Abstract

Introduction: High rates of concurrent gastrointestinal manifestations have been noted in patients with corona virus disease 2019 (COVID-19); however, the association between these digestive manifestations and need for hospitalization has not been established.

Methods: This is a retrospective review of consecutive patients diagnosed with COVID-19. A total of 207 patients were identified; 34.5% of patients noted concurrent gastrointestinal symptoms, with 90% of gastrointestinal symptoms being mild.

Results: In a multivariate regression model controlled for demographics and disease severity, an increased risk of hospitalization was noted in patients with any digestive symptom (adjusted odds ratio 4.84, 95% confidence interval: 1.68-13.94).

Discussion: The presence of digestive symptoms in COVID-19 is associated with a need for hospitalization.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Aged
  • Betacoronavirus
  • COVID-19
  • Coronavirus Infections / complications*
  • Digestive System Diseases / etiology
  • Digestive System Diseases / virology
  • Female
  • Gastrointestinal Diseases / etiology*
  • Gastrointestinal Diseases / virology
  • Hospitalization
  • Humans
  • Male
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / complications*
  • Retrospective Studies
  • SARS-CoV-2