Identification of multiple large deletions in ORF7a resulting in in-frame gene fusions in clinical SARS-CoV-2 isolates

J Clin Virol. 2020 Aug:129:104523. doi: 10.1016/j.jcv.2020.104523. Epub 2020 Jun 23.

Authors

Amin Addetia¹, Hong Xie¹, Pavitra Roychoudhury¹, Lasata Shrestha¹, Michelle Loprieno¹, Meei-Li Huang¹, Keith R Jerome¹, Alexander L Greninger²

Affiliations

¹ Department of Laboratory Medicine, University of Washington, Seattle, WA, USA.
² Department of Laboratory Medicine, University of Washington, Seattle, WA, USA. Electronic address: [email protected].

No abstract available

Publication types

Letter

MeSH terms

Betacoronavirus / genetics*
Betacoronavirus / isolation & purification*
COVID-19
Coronavirus Infections / virology*
Gene Fusion*
Humans
Nasopharynx / virology
Pandemics
Pneumonia, Viral / virology*
SARS-CoV-2
Sequence Analysis, DNA
Sequence Deletion*
Viral Proteins / genetics*

Substances

ORF7a protein, SARS-CoV-2
Viral Proteins