Intravascular schwannoma: A review of a rare diagnosis

J Cutan Pathol. 2021 Feb;48(2):314-317. doi: 10.1111/cup.13797. Epub 2020 Sep 7.

Abstract

While schwannoma is one of the most common types of benign peripheral nerve tumors in adults, a very unique and specific variant of schwannoma, the intravascular variant, is exceedingly rare. There have only been three previously published cases of intravascular schwannomas. Here we describe a fourth case of an intravascular schwannoma in a 47-year-old man with an enlarging subcutaneous nodule on his posterior calf. This is the second case of an intravascular schwannoma contained within a vein. Also included is an overview of intravascular schwannomas, including a description and discussion of the histopathological diagnosis, differential diagnoses, and schwannoma variants.

Keywords: intravascular; intravenous; nerve sheath tumor; neurilemmoma; schwannoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Diagnosis, Differential
  • Humans
  • Male
  • Middle Aged
  • Neurilemmoma / diagnosis*
  • Neurilemmoma / metabolism
  • Neurilemmoma / pathology
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / metabolism
  • Skin Neoplasms / pathology
  • Vascular Neoplasms / diagnosis*
  • Vascular Neoplasms / metabolism
  • Vascular Neoplasms / pathology
  • Veins / metabolism
  • Veins / pathology