Thyroid-Like Follicular Carcinoma of the Kidney With Low-Grade Sarcomatoid Component: A Hitherto Undescribed Case

Int J Surg Pathol. 2021 May;29(3):327-333. doi: 10.1177/1066896920940406. Epub 2020 Jul 10.

Abstract

Thyroid-like follicular carcinoma of the kidney (TLFCK) is a rare subtype of renal cell carcinoma, which closely resembles follicular neoplasms of the thyroid and has a distinctive indolent clinical behavior. Until now, a single case of TLFCK with extensive sarcomatoid differentiation has been documented with aggressive clinical course. We present an unusual case of sarcomatoid TLFCK with a low-grade spindle cell component in a 34-year-old male patient, with an indolent course following radical nephrectomy and regional node dissection.

Keywords: renal cell carcinoma; sarcomatoid; thyroid-like follicular carcinoma of the kidney.

MeSH terms

  • Adenocarcinoma, Follicular / diagnosis
  • Adenocarcinoma, Follicular / secondary
  • Adult
  • Carcinoma, Renal Cell / diagnosis*
  • Carcinoma, Renal Cell / pathology
  • Carcinoma, Renal Cell / surgery
  • Diagnosis, Differential
  • Humans
  • Kidney / pathology*
  • Kidney / surgery
  • Kidney Neoplasms / diagnosis*
  • Kidney Neoplasms / pathology
  • Kidney Neoplasms / surgery
  • Male
  • Nephrectomy
  • Positron Emission Tomography Computed Tomography
  • Thyroid Gland / diagnostic imaging
  • Thyroid Neoplasms / diagnosis
  • Thyroid Neoplasms / pathology