Understanding the Complex Relationship Between Androgens and SARS-CoV2

Urology. 2020 Oct:144:1-3. doi: 10.1016/j.urology.2020.06.048. Epub 2020 Jul 9.

Authors

Jesse Ory¹, Thiago Fernandes Nigres Lima², Maxwell Towe², Fabio Stefano Frech², Jordan C Best², Bruce R Kava², Ranjith Ramasamy³

Affiliations

¹ Department of Urology, Dalhousie University, Halifax, Canada; Department of Urology, Miller School of Medicine, University of Miami, Miami, FL.
² Department of Urology, Miller School of Medicine, University of Miami, Miami, FL.
³ Department of Urology, Miller School of Medicine, University of Miami, Miami, FL. Electronic address: [email protected].

No abstract available

Publication types

Editorial

MeSH terms

Androgen Antagonists / therapeutic use*
Androgen Receptor Antagonists / therapeutic use
Angiotensin-Converting Enzyme 2 / metabolism*
COVID-19 / complications
COVID-19 / prevention & control*
Cardiovascular Diseases / etiology
Humans
Hypoxia / etiology
Male
Oligopeptides / therapeutic use
Prostatic Neoplasms / drug therapy
SARS-CoV-2 / physiology*
Serine Endopeptidases / genetics
Serine Endopeptidases / metabolism*
Systemic Inflammatory Response Syndrome / etiology
Systemic Inflammatory Response Syndrome / prevention & control
Testosterone / adverse effects
Testosterone / deficiency
Testosterone / therapeutic use
Virus Internalization* / drug effects

Substances

Androgen Antagonists
Androgen Receptor Antagonists
Oligopeptides
acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamide
Testosterone
ACE2 protein, human
Angiotensin-Converting Enzyme 2
Serine Endopeptidases
TMPRSS2 protein, human