Chronic nicotine treatment partly protects against the 1-methyl-4-phenyl-2,3,6-tetrahydropyridine-induced degeneration of nigrostriatal dopamine neurons in the black mouse

Acta Physiol Scand. 1988 Apr;132(4):589-91. doi: 10.1111/j.1748-1716.1988.tb08372.x.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
  • Animals
  • Corpus Striatum / drug effects*
  • Corpus Striatum / metabolism
  • Mice
  • Mice, Inbred C57BL
  • Nerve Degeneration / drug effects*
  • Nicotine / administration & dosage*
  • Pyridines / pharmacology*
  • Receptors, Dopamine / drug effects*
  • Substantia Nigra / drug effects*
  • Substantia Nigra / metabolism

Substances

  • Pyridines
  • Receptors, Dopamine
  • Nicotine
  • 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine