Abstract
The in vitro stimulation of T lymphocytes is known to induce the release of factors that possess distinct biological activities. In the present report, we describe the presence, in supernatants of Schistosoma mansoni antigen stimulated T cells from S. mansoni infected patients, of a factor able to inhibit the IgE-dependent platelet cytotoxicity of the same individuals toward the young larvae of S. mansoni.
MeSH terms
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Animals
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Antibody-Dependent Cell Cytotoxicity*
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Blood Platelets / immunology*
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Cell-Free System
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Flow Cytometry
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Humans
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Immunoglobulin E / physiology*
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Larva / immunology
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Lymphocyte Activation
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Schistosoma mansoni / growth & development
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Schistosoma mansoni / immunology*
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Suppressor Factors, Immunologic / physiology*
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T-Lymphocytes / immunology*
Substances
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Suppressor Factors, Immunologic
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Immunoglobulin E