Abstract
Viral infections are common complications of pregnancy, with a wide range of obstetric and neonatal sequelae. Currently, there are limited data on whether SARS-CoV-2 is vertically transmitted in pregnant women tested positive for the virus. Here we describe a case of a known SARS-CoV-2-positive woman giving preterm birth to two fetuses with SARS-CoV-2 positive testing in placental tissue and amniotic fluid. The placental histological examinations showed chronic intervillositis and extensive intervillous fibrin depositions with ischemic necrosis of the surrounding villi.
Keywords:
Pregnancy; SARS-CoV-2; Vertical transmission.
MeSH terms
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Adult
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Amniotic Fluid / virology
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Betacoronavirus / pathogenicity*
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COVID-19
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Cesarean Section
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Coronavirus Infections / diagnosis
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Coronavirus Infections / pathology
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Coronavirus Infections / transmission*
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Coronavirus Infections / virology
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Diabetes, Gestational / diagnosis*
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Diabetes, Gestational / pathology
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Diabetes, Gestational / virology
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Female
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Fetal Death
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Fetus
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Humans
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Infectious Disease Transmission, Vertical*
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Pandemics
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Placenta / pathology
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Placenta / virology
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Pneumonia, Viral / diagnosis
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Pneumonia, Viral / pathology
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Pneumonia, Viral / transmission*
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Pneumonia, Viral / virology
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Pregnancy
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Pregnancy Complications, Infectious / diagnosis*
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Pregnancy Complications, Infectious / pathology
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Pregnancy Complications, Infectious / virology
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Premature Birth / pathology
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Premature Birth / virology*
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SARS-CoV-2
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Twins, Dizygotic