Relevance of Dermabacter hominis isolated from clinical samples, 2012-2016: a retrospective case series

Cédéric Schaub; Sarah Dräger; Vladimira Hinic; Stefano Bassetti; Reno Frei; Michael Osthoff

doi:10.1016/j.diagmicrobio.2020.115118

Relevance of Dermabacter hominis isolated from clinical samples, 2012-2016: a retrospective case series

Diagn Microbiol Infect Dis. 2020 Oct;98(2):115118. doi: 10.1016/j.diagmicrobio.2020.115118. Epub 2020 Jun 24.

Authors

Cédéric Schaub¹, Sarah Dräger², Vladimira Hinic³, Stefano Bassetti⁴, Reno Frei⁵, Michael Osthoff⁶

Affiliations

¹ Division of Internal Medicine, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland. Electronic address: [email protected].
² Department of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland. Electronic address: [email protected].
³ Division of Clinical Bacteriology and Mycology, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland. Electronic address: [email protected].
⁴ Division of Internal Medicine, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland; Department of Clinical Research, University Basel, Hebelstrasse 20, 4031 Basel, Switzerland. Electronic address: [email protected].
⁵ Department of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland. Electronic address: [email protected].
⁶ Division of Internal Medicine, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland; Department of Clinical Research, University Basel, Hebelstrasse 20, 4031 Basel, Switzerland. Electronic address: [email protected].

PMID: 32683204
DOI: 10.1016/j.diagmicrobio.2020.115118

Abstract

We investigated the clinical relevance of Dermabacter hominis isolated from samples of 108 patients. Polymicrobial growth was evident in 88% of specimens. Isolation of D. hominis was of definitive or possible significance in only 14% of patients. Vancomycin remains the drug of choice given a penicillin resistance rate of 84%.

Keywords: Clinical significance; Dermabacter hominis; Gram-positive rod; Isolation; Vancomycin.

MeSH terms

Actinobacteria / classification*
Actinobacteria / drug effects
Actinobacteria / isolation & purification
Actinomycetales / classification*
Actinomycetales / drug effects
Actinomycetales / isolation & purification
Actinomycetales Infections / drug therapy
Actinomycetales Infections / microbiology*
Adult
Aged
Aged, 80 and over
Anti-Bacterial Agents / therapeutic use
Bacterial Typing Techniques
DNA, Bacterial
Drug Resistance, Bacterial
Female
Humans
Male
Middle Aged
Penicillins / pharmacology
Retrospective Studies
Vancomycin / pharmacology

Substances

Anti-Bacterial Agents
DNA, Bacterial
Penicillins
Vancomycin

Supplementary concepts

Dermabacter hominis