False-negative RT-PCR in SARS-CoV-2 disease: experience from an Italian COVID-19 unit

Marcello Di Paolo; Alessandra Iacovelli; Federica Olmati; Ilaria Menichini; Alessandra Oliva; Martina Carnevalini; Elda Graziani; Claudio Maria Mastroianni; Paolo Palange

doi:10.1183/23120541.00324-2020

False-negative RT-PCR in SARS-CoV-2 disease: experience from an Italian COVID-19 unit

ERJ Open Res. 2020 Jul 13;6(2):00324-2020. doi: 10.1183/23120541.00324-2020. eCollection 2020 Apr.

Authors

Marcello Di Paolo¹, Alessandra Iacovelli¹, Federica Olmati¹, Ilaria Menichini¹, Alessandra Oliva¹, Martina Carnevalini¹, Elda Graziani¹, Claudio Maria Mastroianni¹, Paolo Palange¹

Affiliation

¹ Dept of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.

Abstract

False-negative cases of #COVID19 are being increasingly reported. Laboratory diagnosis through RT-PCR testing alone lacks adequate sensitivity to be recommended as the only valid criterion to confirm COVID-19 diagnosis. https://bit.ly/2BLFnEe.