One novel pentacyclic triterpene, 24-dimethoxymethyl-3β,6β,19α- trihydroxy -12-en-28-oic acid (1), along with six known compounds 2-7, were isolated from the canes of Uncaria sessilifructus Roxb. Their structures were determined according to spectroscopic and spectrometric analysis. The anti-inflammatory activities of the isolated compounds (1-7) were scanned against NO production in LPS-activated RAW 264.7 macrophages by MTS assay, however no activities were observed.
Keywords: Uncaria sessilifructus; anti-inflammatory activity; pentacyclic triterpene.