Long-acting reversible contraception side effect management

Curr Opin Pediatr. 2020 Aug;32(4):461-470. doi: 10.1097/MOP.0000000000000930.

Abstract

Purpose of review: Long-acting reversible contraception (LARC) is increasingly used by adolescents and young adults (AYAs). Subsequent to LARC insertion, AYAs are presenting to their primary care providers with LARC concerns. This article seeks to equip primary care clinicians with the tools necessary to assess and manage common LARC-associated side effects.

Recent findings: Side effects are common with progestin-only LARC, and can precipitate early discontinuation of an otherwise effective, low-maintenance form of contraception. Abnormal uterine bleeding, pelvic pain, acne, and weight change are often cited as progestin-only LARC side effects, yet the causes are poorly understood despite extensive research. While most side effects improve with time, therapeutic interventions are available for patients with undesirable side effects that prefer medical management. Research emphasizes the importance of proper patient counseling and clinical follow-up.

Summary: Counseling remains essential in the management of LARC-associated side effects. However, options are available to temporarily mitigate such side effects and increase LARC satisfaction. While these therapeutic options are prescribed based on expert opinion, such regimens remain inadequately studied in AYA populations.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Acne Vulgaris / chemically induced*
  • Adolescent
  • Contraception
  • Counseling
  • Drug-Related Side Effects and Adverse Reactions*
  • Female
  • Humans
  • Long-Acting Reversible Contraception / adverse effects*
  • Pregnancy
  • Pregnancy in Adolescence / prevention & control*
  • Uterine Hemorrhage / chemically induced*
  • Weight Gain
  • Young Adult