A Biliary Mucinous Cystic Neoplasm with Intrahepatic and Lymph Node Metastases

Intern Med. 2020 Nov 15;59(22):2891-2896. doi: 10.2169/internalmedicine.4816-20. Epub 2020 Jul 21.

Abstract

A 51-year-old woman who presented with a large cystic liver tumor with mural nodules in the lateral segment developed Trousseau's syndrome. A mural nodule directly invaded her liver parenchyma. Metastatic nodules were detected in the right lobe and portal/paraaortic lymph nodes. The pathological findings showed mucin-producing adenocarcinoma cells to have invaded the fibrous stroma forming a micropapillary cluster. She developed obstructive jaundice due to tumor progression and subsequently died of hepatic failure. Invasive biliary mucinous cystic neoplasm (MCN) is a rare form of a malignant tumor with a relatively favorable prognosis. This is a very rare case biliary MCN with invasive carcinoma that showed intrahepatic and lymph node metastases.

Keywords: biliary mucinous cystic neoplasm; intrahepatic metastasis; lymph node metastasis.

Publication types

  • Case Reports

MeSH terms

  • Biliary Tract Neoplasms*
  • Carcinoma*
  • Female
  • Humans
  • Liver Neoplasms*
  • Lymphatic Metastasis
  • Middle Aged
  • Prognosis