Anti-proliferative activity and characterization data on oxadiazole derivatives

Dukanya; Muthu K Shanmugam; Shobith Rangappa; Prashant K Metri; Surender Mohan; Basappa; Kanchugarakoppal S Rangappa

doi:10.1016/j.dib.2020.105979

Anti-proliferative activity and characterization data on oxadiazole derivatives

Data Brief. 2020 Jul 3:31:105979. doi: 10.1016/j.dib.2020.105979. eCollection 2020 Aug.

Authors

Dukanya¹, Muthu K Shanmugam², Shobith Rangappa³, Prashant K Metri¹, Surender Mohan¹, Basappa¹, Kanchugarakoppal S Rangappa⁴

Affiliations

¹ Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Manasagangotri, Mysore 570006, India.
² Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore 117600, Singapore.
³ Adichunchanagiri Institute for Molecular Medicine, BG Nagara-571448, Nagamangala Taluk, Mandya District, India.
⁴ Institution of Excellence, VijnanaBhavan, University of Mysore, Manasagangotri, Mysore 570006, India.

Abstract

This data in brief article explains the anti-cancer activity and characterization of oxadiazoles [1]. The main objective of this article was to provide general synthetic procedures, spectral discussion and physical data on the new oxadiazole tethered indazole (OTDs). This article discusses the ¹H NMR, ¹³C NMR, mass spectroscopy, HPLC and melting point of the synthetic compounds. MTT assay was used to determine the anti-proliferative activity in hepatocellular cell lines.

Keywords: Anti-cancer; Characterization; Indazole; MTT assay.