Structural insights into the activation of GLP-1R by a small molecule agonist

Cell Res. 2020 Dec;30(12):1140-1142. doi: 10.1038/s41422-020-0384-8. Epub 2020 Jul 28.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cryoelectron Microscopy
  • Cyclic AMP / metabolism
  • Glucagon-Like Peptide-1 Receptor / agonists*
  • Glucagon-Like Peptide-1 Receptor / chemistry*
  • Glucagon-Like Peptide-1 Receptor / ultrastructure
  • Models, Molecular
  • Protein Domains
  • Small Molecule Libraries / pharmacology*
  • Structural Homology, Protein

Substances

  • Glucagon-Like Peptide-1 Receptor
  • Small Molecule Libraries
  • Cyclic AMP