Interpretation pitfalls and malignant mimics in cervical cytology

J Am Soc Cytopathol. 2021 Mar-Apr;10(2):115-127. doi: 10.1016/j.jasc.2020.06.005. Epub 2020 Jun 25.

Abstract

Cervical cytology has remained a diagnostically challenging area despite its long and widespread use. At least part of this challenge has stemmed from the cytomorphologic overlap between benign and neoplastic processes. The present review has highlighted select benign processes that present diagnostic pitfalls. For each of these, we have discussed the pertinent cytologic features and emphasized the morphologic clues that will aid in distinguishing the benign entities from the neoplastic processes they mimic.

Keywords: Cervical cytology; Intrauterine device; Pap smear; Pitfalls; Tubal metaplasia.

Publication types

  • Review

MeSH terms

  • Cervix Uteri / cytology*
  • Cervix Uteri / pathology
  • Diagnosis, Differential
  • Female
  • Humans
  • Uterine Cervical Diseases / diagnosis*
  • Uterine Cervical Diseases / pathology
  • Uterine Cervical Neoplasms / diagnosis*
  • Uterine Cervical Neoplasms / pathology