Increased Risk of Acquisition of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) among a Cohort of COVID-19 Patients in a Teaching Hospital in Tuscany, Italy

Andrea Davide Porretta; Angelo Baggiani; Guglielmo Arzilli; Virginia Casigliani; Tommaso Mariotti; Francesco Mariottini; Giuditta Scardina; Daniele Sironi; Michele Totaro; Simona Barnini; Gaetano Pierpaolo Privitera

doi:10.3390/pathogens9080635

Increased Risk of Acquisition of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) among a Cohort of COVID-19 Patients in a Teaching Hospital in Tuscany, Italy

Pathogens. 2020 Aug 5;9(8):635. doi: 10.3390/pathogens9080635.

Affiliations

¹ Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56123 Pisa, Italy.
² University Hospital of Pisa, 56123 Pisa, Italy.
³ Bacteriology Unit, University Hospital of Pisa, 56123 Pisa, Italy.

Abstract

We describe the epidemiology of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) colonization/infection in a cohort of COVID-19 patients in an Italian teaching hospital. These patients had an increased risk of NDM-CRE acquisition versus the usual patients (75.9 vs. 25.3 cases/10,000 patient days). The co-infection significantly increased the duration of hospital stay (32.9 vs. 15.8 days).

Keywords: COVID-19; New Delhi metallo-beta-lactamase; health care related infections; surveillance.