Predictive value of bubble sign for tubal patency during office hysteroscopy

Judit Lörincz; Szabolcs Molnár; Tünde Herman; Salvatore Giovanni Vitale; Singh Jashanjeet; Rudolf Lampé; László Kardos; Péter Török

doi:10.1016/j.ejogrb.2020.07.048

Predictive value of bubble sign for tubal patency during office hysteroscopy

Eur J Obstet Gynecol Reprod Biol. 2020 Oct:253:58-60. doi: 10.1016/j.ejogrb.2020.07.048. Epub 2020 Jul 29.

Authors

Judit Lörincz¹, Szabolcs Molnár², Tünde Herman³, Salvatore Giovanni Vitale⁴, Singh Jashanjeet⁵, Rudolf Lampé⁶, László Kardos⁷, Péter Török⁸

Affiliations

¹ Department of Obstetrics and Gynecology, Univesity of Debrecen, Faculty of Medicine, Hungary. Electronic address: [email protected].
² Department of Obstetrics and Gynecology, Univesity of Debrecen, Faculty of Medicine, Hungary. Electronic address: [email protected].
³ Center for Assisted Reproduction, University of Debrecen Clinical Center, Hungary. Electronic address: [email protected].
⁴ Obstetrics and Gynecology Unit, Department of General Surgery and Medical Surgical Specialties, University of Catania, Italy.
⁵ Department of Obstetrics and Gynecology, Univesity of Debrecen, Faculty of Medicine, Hungary. Electronic address: [email protected].
⁶ Department of Obstetrics and Gynecology, Univesity of Debrecen, Faculty of Medicine, Hungary. Electronic address: [email protected].
⁷ University of Debrecen, Kenézy Gyula Teaching Hospital, Department of Clinical Pharmacology, Infectology and Allergology, Hungary. Electronic address: [email protected].
⁸ Department of Obstetrics and Gynecology, Univesity of Debrecen, Faculty of Medicine, Hungary. Electronic address: [email protected].

PMID: 32777542
DOI: 10.1016/j.ejogrb.2020.07.048

Abstract

Objective: Our purpose was to investigate the predictive value of visible air bubble sign for real tubal patency during hysteroscopic procedures.

Methods: In this cross-sectional study, clinical data of 61 infertile women who underwent diagnostic hysteroscopy and laparoscopy have been analysed.

Results: Mean age of patients was 33.45 ± 3.25 years. Bubble sign for the detection of patency demonstrated 73 % (95 % CI: 57-86 %) sensitivity, 70 % (95 % CI: 46-88 %) specificity, a positive predictive value of 83 % (95 % CI: 67-94 %), and a negative predictive value of 56 % (95 % CI: 35-76 %).

Conclusions: A visible tubal "flow" of air bubbles during hysteroscopy was not accurate in the prediction of tubal patency.

Keywords: Bubble sign; Fallopian tubes; Hysteroscopy; Infertility; Laparoscopy; Tubal patency.

MeSH terms

Adult
Cross-Sectional Studies
Fallopian Tube Patency Tests
Fallopian Tubes / diagnostic imaging
Female
Humans
Hysterosalpingography
Hysteroscopy
Infertility, Female* / diagnostic imaging
Laparoscopy*
Pregnancy
Sensitivity and Specificity