Dataset on blood flow and instantaneous wave-free ratio in normal and stenosed coronary arteries

Haipeng Liu; Shanxing Ou; Panli Liu; Yuhang Xu; Yinglan Gong; Ling Xia; Xinyi Leng; Thomas Wai Hong Leung; Lin Shi; Dingchang Zheng

doi:10.1016/j.dib.2020.106011

Dataset on blood flow and instantaneous wave-free ratio in normal and stenosed coronary arteries

Data Brief. 2020 Jul 11:32:106011. doi: 10.1016/j.dib.2020.106011. eCollection 2020 Oct.

Authors

Haipeng Liu¹, Shanxing Ou², Panli Liu³, Yuhang Xu¹, Yinglan Gong⁴, Ling Xia⁴, Xinyi Leng⁵, Thomas Wai Hong Leung⁵, Lin Shi⁶, Dingchang Zheng¹

Affiliations

¹ Research Centre of Intelligent Healthcare, Faculty of Health and Life Science, Coventry University, Coventry CV1 5FB, UK.
² Department of Radiology, General Hospital of Southern Theater Command, PLA, Guangzhou, China.
³ Department of Radiology, Guangzhou First People's Hospital, Nansha Hospital, Guangzhou, China.
⁴ Department of Biomedical Engineering, Zhejiang University, Hangzhou, China.
⁵ Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China.
⁶ Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China.

Abstract

Instantaneous wave-free ratio (iFR) has been proposed as a hemodynamic parameter that can reliably reflect the blood flow in stenosed coronary arteries. Currently, there are few investigations on the quantitative analysis of iFR in the patients regarding the variation of microcirculatory resistance (MR). The data aim to provide geometric (cross-section area of branches) and hemodynamic (flow rate and iFR of branches) parameters of normal and stenosed coronary arteries derived from CFD simulation. The CFD simulation was performed on the three-dimensional artery models reconstructed from computed tomography (CT) images of four subjects. The hemodynamic parameters were obtained in six situations of MR to simulate coronary microvascular dysfunction (CMD). This dataset could be used as the reference to estimate the iFR and flow rate in patients with CMD and stenosis in coronary arteries. The geometric parameters could be used in the modelling of coronary arteries.

Keywords: Computational fluid dynamics (CFD); Coronary artery disease (CAD); Coronary microvascular dysfunction (CMD); Instantaneous wave-free ratio (iFR).