Acute effect of ambient air pollution on hospital outpatient cases of chronic sinusitis in Xinxiang, China

Ecotoxicol Environ Saf. 2020 Oct 1:202:110923. doi: 10.1016/j.ecoenv.2020.110923. Epub 2020 Jul 7.

Abstract

Many studies have reported that exposure to ambient air pollution has adverse effects on health. However, there are little researches to explore the relationship between ambient air pollution and chronic sinusitis (CS). From January 1 2015 to December 31 2018, a time-series study were carried out to investigate the acute adverse roles of six criteria ambient air pollutants (fine particulate matter [PM2.5], inhalable particulate matter [PM10], nitrogen dioxide [NO2], sulfur dioxide [SO2], ozone [O3], and carbon monoxide [CO]) in hospital outpatients with CS in Xinxiang, China. Then, an over-dispersed Poisson generalized additive model was utilized to analyzed the relationships. In total, 183,943 hospital outpatient cases of CS were identified during the study period. We found that a 10 μg/m3 increase in PM2.5, PM10, SO2, NO2, and CO corresponded to 0.48% (95% confidence interval: 0.22-0.74%), 0.33% (0.16-0.50%), 0.88% (0.13-1.62%), 1.98% (1.31-2.64%), and 0.05% (0.03-0.07%) increments, respectively, in CS outpatients on the current day. The young group (<15 years of age) was more susceptible than the adult or elderly groups. These results suggested that outdoor air pollutants might increase CS outpatient, especially among youth in Xinxiang. Precautions and protective measures should be strengthened to reduce the air pollution level in the future.

Keywords: Air pollution; Chronic sinusitis; Hospital outpatients; Time-series study; Young group.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Air Pollutants / analysis
  • Air Pollutants / toxicity*
  • Air Pollution / adverse effects
  • Air Pollution / statistics & numerical data*
  • Carbon Monoxide / analysis
  • China / epidemiology
  • Chronic Disease
  • Female
  • Humans
  • Inhalation Exposure / statistics & numerical data*
  • Male
  • Nitrogen Dioxide / analysis
  • Outpatients
  • Ozone / analysis
  • Particulate Matter / analysis
  • Sinusitis / chemically induced
  • Sinusitis / epidemiology*
  • Sulfur Dioxide / analysis
  • Young Adult

Substances

  • Air Pollutants
  • Particulate Matter
  • Sulfur Dioxide
  • Ozone
  • Carbon Monoxide
  • Nitrogen Dioxide