Lopinavir-Ritonavir Treatment for COVID-19 Infection in Intensive Care Unit: Risk of Bradycardia

Circ Arrhythm Electrophysiol. 2020 Aug;13(8):e008798. doi: 10.1161/CIRCEP.120.008798. Epub 2020 Jul 9.
No abstract available

Keywords: COVID-19; bradycardia; critical illness; humans; lopinavir; ritonavir.

Publication types

  • Letter

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Antiviral Agents / adverse effects*
  • Antiviral Agents / pharmacokinetics
  • Betacoronavirus / drug effects*
  • Betacoronavirus / pathogenicity
  • Bradycardia / chemically induced*
  • Bradycardia / diagnostic imaging
  • Bradycardia / physiopathology
  • COVID-19
  • COVID-19 Drug Treatment
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / drug therapy*
  • Coronavirus Infections / virology
  • Drug Combinations
  • Female
  • Heart Rate / drug effects*
  • Humans
  • Intensive Care Units*
  • Lopinavir / adverse effects*
  • Lopinavir / pharmacokinetics
  • Male
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / drug therapy*
  • Pneumonia, Viral / virology
  • Prospective Studies
  • Risk Assessment
  • Risk Factors
  • Ritonavir / adverse effects*
  • Ritonavir / pharmacokinetics
  • SARS-CoV-2
  • Time Factors
  • Treatment Outcome

Substances

  • Antiviral Agents
  • Drug Combinations
  • lopinavir-ritonavir drug combination
  • Lopinavir
  • Ritonavir