Lung DNA Methylation in Chronic Obstructive Pulmonary Disease: Relationship with Smoking Status and Airflow Limitation Severity

Sandra Casas-Recasens; Guillaume Noell; Nuria Mendoza; Alejandra Lopez-Giraldo; Tamara Garcia; Angela Guirao; Alvar Agusti; Rosa Faner

doi:10.1164/rccm.201912-2420LE

Lung DNA Methylation in Chronic Obstructive Pulmonary Disease: Relationship with Smoking Status and Airflow Limitation Severity

Am J Respir Crit Care Med. 2021 Jan 1;203(1):129-134. doi: 10.1164/rccm.201912-2420LE.

Authors

Sandra Casas-Recasens¹, Guillaume Noell^{1

2}, Nuria Mendoza², Alejandra Lopez-Giraldo^{1

2

3}, Tamara Garcia¹, Angela Guirao^{1

2

3}, Alvar Agusti^{1

2

3

4}, Rosa Faner^{1

2}

Affiliations

¹ Centro de Investigación Biomédica en Red de Enfermedades Respiratorias Madrid, Spain.
² Institut d'Investigacions Biomediques August Pi i Sunyer Barcelona, Spain.
³ Hospital Clinic of Barcelona Barcelona, Spain and.
⁴ University of Barcelona Barcelona, Spain.

PMID: 32822219
DOI: 10.1164/rccm.201912-2420LE

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Aged
DNA Methylation*
Female
Forced Expiratory Volume / genetics*
Forced Expiratory Volume / physiology*
Gene Expression Regulation
Humans
Lung / physiopathology*
Male
Middle Aged
Pulmonary Disease, Chronic Obstructive / genetics*
Pulmonary Disease, Chronic Obstructive / physiopathology*
Smoking / genetics*
Smoking / physiopathology