"Double hit" anaplastic large cell lymphoma with concurrent ALK and MYC rearrangements

Am J Hematol. 2020 Dec;95(12):1625-1627. doi: 10.1002/ajh.25980. Epub 2020 Sep 12.

Authors

David X Luo¹, Wuping Li^{1

2}, Mathew T Ye¹, Yaling Yang¹, Guilin Tang¹, M James You¹

Affiliations

¹ Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
² Department of Lymphoma & Myeloma, Jiangxi Cancer Hospital, Nanchang, China.

PMID: 32833271
DOI: 10.1002/ajh.25980

No abstract available

Publication types

Case Reports

MeSH terms

Adult
Anaplastic Lymphoma Kinase / genetics*
Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
Cyclophosphamide / administration & dosage
Doxorubicin / administration & dosage
Gene Rearrangement*
Humans
Lymphoma, Large-Cell, Anaplastic* / diagnostic imaging
Lymphoma, Large-Cell, Anaplastic* / drug therapy
Lymphoma, Large-Cell, Anaplastic* / genetics
Lymphoma, Large-Cell, Anaplastic* / pathology
Male
Positron Emission Tomography Computed Tomography*
Prednisone / administration & dosage
Proto-Oncogene Proteins c-myc / genetics*
Vincristine / administration & dosage

Substances

MYC protein, human
Proto-Oncogene Proteins c-myc
Vincristine
Doxorubicin
Cyclophosphamide
ALK protein, human
Anaplastic Lymphoma Kinase
Prednisone

Supplementary concepts

CHOP protocol