Plasma C3d levels as a diagnostic marker for complete complement factor I deficiency

Affiliations

• ¹ Primary Immunodeficiency Research Lab, Center for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium; Department of Hematology, Center for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium.
• ² Belgian National Reference Center for the Complement System, Laboratory of Immunology, LHUB-ULB, Université Libre de Bruxelles, Brussels, Belgium.
• ³ Primary Immunodeficiency Research Lab, Center for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium; Laboratory of Immunoregulation, VIB Inflammation Research Center, Ghent, Belgium.
• ⁴ Department of Pediatrics, Division of Pediatric Pulmonology, Infectious Diseases and Immunology, Ghent University Hospital, Ghent, Belgium.
• ⁵ Primary Immunodeficiency Research Lab, Center for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium; Department of Pediatrics, Division of Pediatric Pulmonology, Infectious Diseases and Immunology, Ghent University Hospital, Ghent, Belgium.
• ⁶ Division of Laboratory Medicine, Department of Clinical Chemistry, Ghent University Hospital, Ghent, Belgium.
• ⁷ Department of Pediatrics, Division of Pediatric Neurology, University Hospital Ghent, Ghent, Belgium.
• ⁸ Department of Pediatrics, Division of Pediatric Oncology and Immunology, Universitair Ziekenhuis Brussel, Jette, Belgium.
• ⁹ Department of Pediatrics, Department of Haematology-Oncology, Children's University Hospital Queen Fabiola, Université Libre de Bruxelles, Brussels, Belgium.
• ¹⁰ Department of Human Genetics, Institut de Pathologie et Génétique, Gosselies, Belgium.
• ¹¹ Department of Hematology, Center for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium.
• ¹² Department of Pediatrics, Division of Pediatric Nephrology, University Hospital Ghent, Ghent, Belgium.
• ¹³ Department of Pediatrics, Division of Pediatric Nephrology, The Hospital for Sick Children, Toronto, Ontario, Canada.
• ¹⁴ Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, Université de Paris, Paris, France.
• ¹⁵ Primary Immunodeficiency Research Lab, Center for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium; Department of Pediatrics, Division of Pediatric Pulmonology, Infectious Diseases and Immunology, Ghent University Hospital, Ghent, Belgium. Electronic address: [email protected].